in determining the optimal dose of thyroxine, the biochemical target is a TSH result that is detectable, not elevated, and preferably within the reference range.The risk of over suppression of TSH is an increased risk of atrial fibrillation and osteoporosis.
A TSH result of less than 0.1 should be considered as undetectable and consideration should be given to reducing the dose of levothyroxine.
However, TSH should be fully suppressed in patients who have had thyroid cancer.
However, TSH should be fully suppressed in patients who have had thyroid cancer.
Source: letter from Dr Doug Black 17th January 2011
